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Mesothelioma<br><br>Mesothelioma is a cancer that grows in the linings that protect organs such as the chest and abdomen. It is typically caused by asbestos exposure, particularly for those working in industrial or construction work.<br><br>Early diagnosis and treatment are crucial to a favorable prognosis. Patients suffering from mesothelioma will have better outcomes if they are diagnosed before the disease has spread.<br><br>Causes<br><br>Mesothelioma an aggressive cancerous tumor that forms in the tissue of the abdomen and chest is a rare condition. In most cases, mesothelioma that is malignant is found in the lung's lining (the pleura) or the stomach's lining and the intestines (the peritoneum). However, it can also be found in other tissues, such as the tissue that surrounds the heart (pericardial mesothelioma) and the testicles (tunica vaginalis mesothelioma).<br><br>The exposure to asbestos is the most significant cause of mesothelioma. Asbestos is an assortment of minerals that contain tiny, microscopic fibers. Asbestos was widely used in many industries, such as shipbuilding, construction, and insulation. Anyone exposed to asbestos can develop mesothelioma symptoms up to 40 years after their first exposure to asbestos.<br><br>The most common mesothelioma sign is difficulty breathing. This is caused by a buildup within the space between lungs and the chest wall. Doctors can detect mesothelioma by studying a patient's medical record and doing diagnostic tests. They will review the patient's X-rays, computed-tomography (CT), and magnetic resonance imaging scans (MRI) to determine whether there is any evidence of asbestos exposure.<br><br>A biopsy is used to diagnose pleural msothelioma. During the procedure, doctors will collect a small amount of tissue from the affected area and examine it under microscope. A biopsy is performed using two methods: VATS (Video-assisted thoracoscopic surgery), a type of keyhole surgery or a needle that's inserted into a CT scan.<br><br>Mesothelioma can be difficult to recognize because the signs and symptoms are similar to other diseases. It is crucial to speak with an expert when you begin to notice any signs.<br><br>When mesothelioma begins to manifest it's usually at an advanced stage. This means that treatment options will be limited. Most patients who have mesothelioma lung suffer from complications of the disease, which include respiratory failure and pneumonia. Patients who have mesothelioma in different organs, like pericardial [https://botdb.win/wiki/What_Is_Mesothelioma_Settlement_And_How_To_Use_What_Is_Mesothelioma_Settlement_And_How_To_Use Mesothelioma Lawyers] or tunica vaginalis may die from complications affecting the heart or bowel.<br><br>Signs and symptoms<br><br>It can be difficult for doctors diagnose [https://pediascape.science/wiki/10_Wrong_Answers_To_Common_Mesothelioma_Compensation_Questions_Do_You_Know_The_Correct_Answers mesothelioma litigation] because many of its symptoms are similar to other diseases or conditions. Patients might be asked about their exposure to asbestos. They may also request an X-ray of the chest or CT scan to identify problems with the lungs and chest. The next step is usually a biopsy, where doctors collect a small amount of tissue to test for mesothelioma. A biopsy can be used to determine if the cancer cells are malignant.<br><br>Pleural mesothelioma develops in the lung's lining, and the signs are typically breathing shortness and pain that gets worse over time. These symptoms could also be caused by the accumulation of fluid in the lung (pleural effusion). Other signs of pleural [https://harpsheet9.werite.net/why-mesothelioma-claim-is-harder-than-you-imagine mesothelioma settlement] include bloody coughing, abdominal swelling, weight loss, fatigue, and breathing problems. Peritoneal mesothelioma is a rarer form of me, and it typically causes symptoms such as abdominal discomfort, nausea as well as fatigue and fever. Even less common is mesothelioma in the tunica vaginalis that can cause testicular pain and a lump on the scrotum and loss of appetite.<br><br>Doctors will treat mesothelioma when it has spread to other areas of the body. They will use various treatments and tests. They can use surgery and chemotherapy and radiation therapy as well as immunotherapy to kill [https://hein-woods-2.mdwrite.net/20-things-you-must-be-educated-about-the-best-mesothelioma-law-firm-1718270641/ mesothelioma] cancer cells or keep them from growing. These treatments are available in a hospital, at home, or through a clinic.<br><br>A biopsy can help doctors determine the mesothelioma type the patient has. There are three main mesothelioma cells types: epithelioid and sarcomatoid and biphasic. The most popular mesothelioma type is epithelioid. They grow more slowly than other cancerous cells and are therefore more manageable. Sarcomatoid cancer is more difficult to cure and can spread rapidly.<br><br>A patient with mesothelioma needs to seek immediate treatment if they notice any signs or symptoms. It is imperative that they seek treatment immediately if they experience any symptoms. A misdiagnosis could prevent them from receiving the right treatment and prolong cancer time to develop. Patients who have mesothelioma treated intensive treatment have a better chances of living a longer life.<br><br>Diagnosis<br><br>Mesothelioma is a rare type of cancer, so it can be difficult to diagnose. It may take a few weeks or even months for doctors to determine that a patient is suffering from a condition that requires treatment. The doctor will also inquire about the patient's asbestos exposure and the date when symptoms started. The doctor may also request an imaging scan. These tests can help determine areas of issue with the lungs as well as the chest cavity.<br><br>A biopsy is the principal test to diagnose mesothelioma. It involves taking tiny pieces of the tumor, then looking at it under a magnifying glass. The specialist doctor will be able determine if the tumor is mesothelioma and also the type.<br><br>There are three types: sarcomatoid, mixed (biphasic) or epithelioid. The type of cells can impact how well the tumor can be treated. Epithelioid cell types are the most common, found in about 70 percent of mesothelioma patients. Sarcomatoid cancer cells are similar to the ones found in fibrous tissue. They are found in 30percent of mesothelioma cases. The most deadly mesothelioma variant, called mixed mesothelioma occurs when it has epithelioid as well as sarcomatoid cancer cells.<br><br>A blood test is a way to see if levels of fibulin-3, osteopontin and soluble mesothelin peptides that are elevated in the body. These substances are usually higher in mesothelioma patients, but not in other people. The results of these tests are not conclusive in either proving or disproving a diagnosis.<br><br>The doctor can also order other tests if a mesothelioma has been identified to determine the extent to which the cancer has spread and how it affects the health of the patient. For instance the lung function test will show how the lungs are functioning and assist doctors in deciding whether surgery is an option.<br><br>Other tests include an CT scan or MRI. A PET-CT scan combines an CT scan with a positron emission scanner, which allows doctors to find out if the cancer has taken hold and where it's located. The doctor could also order an echocardiogram, which will look at an increase in the volume of blood around the heart.<br><br>Treatment<br><br>Patients suffering from mesothelioma must find the appropriate treatment for their condition. Treatment options include radiation, chemotherapy and immunotherapy. To receive the best possible care, patients should work in a team at an experienced mesothelioma clinic within their area.<br><br>Doctors are able to diagnose Mesothelioma using physical examinations, laboratory tests, and imaging scans. A patient can be referred to a specialist for more in-depth testing or for treatment options, such as a biopsy. A biopsy is the removal of a small piece of tissue to be examined under a microscope. Mesothelioma (a cancerous growth that is found in the mesothelium (a protective layer of cells that covers organs in the abdomen and chest) is a form of cancer. It can spread into the bloodstream, and then travel to other parts in the body, where it may cause serious complications.<br><br>In addition to a biopsy, physicians may conduct a CT scan or an MRI of the chest and abdomen. These imaging tests are used to detect signs of mesothelioma or other diseases. They can also show how the tumor is affecting surrounding organs, like how a mesothelioma in the lungs affects the heart and intestines.<br><br>Blood tests can detect mesothelioma through the detection of a substance found in blood. These tests aren't always reliable, and cannot replace a biopsy for mesothelioma. Mesothelioma can be detected at an early stage, which is important to help increase survival rates.<br><br>There are three types of mesothelioma depending on the kind of cells that make up. Epithelioid is the most frequent kind and is the most responsive to treatment. Biphasic and Sarcomatoid mesothelioma are less responsive to treatment and have a worse prognosis.<br><br>Malignant pleural melanoma is found in the lining of the lungs, called the pleura. Doctors can treat pleural mesothelioma by undergoing surgery or chemotherapy. The mesothelioma type can be treated using two different surgeries: extrapleural pulmonary pneumonectomy (EPP) and pleurectomy/pericardiectomy (P/D).<br><br>Doctors may opt for hyperthermic intraoperative chemotherapy (HIOC) HIOC to reduce the risk of cancer recurrence after surgery. During HIOC doctors inject chemotherapy drugs that fight cancer directly into the surgical site. The patient is then rocked around to bathe the area in hot chemotherapy fluids.
Mesothelioma<br><br>Mesothelioma is a form of cancer that grows in the linings of protection around organs, such as the abdomen and chest. It is usually caused by asbestos exposure, particularly for those working in industrial or construction jobs.<br><br>Early diagnosis and treatment are essential to a favorable prognosis. If mesothelioma can be detected early the patients are more likely to be successful.<br><br>Causes<br><br>Mesothelioma is a type of cancer that develops in the tissue which lines the chest and abdomen. In the majority of instances, [https://mmatycoon.info/index.php/10_Quick_Tips_For_Mesothelioma_Law mesothelioma litigation] is malignant and is found in the lining of the lungs (the pleura) or the stomach's lining and the intestines (the peritoneum). It can also affect other tissues such as the tissues surrounding the heart (pericardial msothelioma), and the testicles.<br><br>Asbestos exposure is the main cause of mesothelioma. Asbestos is an assortment of minerals that contain tiny, microscopic fibers. Asbestos used to be widely utilized in many industries, including construction, shipbuilding and insulation. Asbestos exposure may cause mesothelioma symptoms for as long as 40 years after the last exposure.<br><br>The most commonly reported symptoms is difficulty breathing. This is caused by an accumulation of fluid in the space between the lungs and the chest wall. Doctors can identify the disease by reviewing the medical records of a patient as well as conducting diagnostic tests. They will look at the patient's X rays, computed-tomography (CT), and magnetic resonance imaging scans (MRI) to determine whether there is any evidence of asbestos exposure.<br><br>A biopsy is the main method used to detect mesothelioma pleural. In the course of the test, doctors will collect a small amount of tissue from the affected area to examine under the microscope. A biopsy can be carried out using two methods: VATS, a type keyhole surgery. Or, a needle that is inserted through a CT scan.<br><br>The signs and symptoms of mesothelioma are similar to those of other cancers which makes it difficult to determine. It's important to consult a doctor as soon as you notice any symptoms.<br><br>When mesothelioma first gets diagnosed, it's often in an advanced stage. Treatment options are limited. The majority of patients with mesothelioma of the lung die from complications of the disease, which include pneumonia and respiratory failure. Patients who have mesothelioma in different organs such as pericardial mesothelioma or tunica vaginalis may suffer complications that affect the heart or bowel.<br><br>Symptoms<br><br>Many of the symptoms of mesothelioma are comparable to the symptoms of other diseases or conditions that is why it may be difficult for doctors to establish a diagnosis. Patients might be asked about their exposure to asbestos. They can also request a chest X-ray or CT scan to look for problems with the lungs and chest. A biopsy is typically the next step. It is where doctors take a small portion of mesothelioma to test. A biopsy can be used to determine whether the cancerous cells are malignant.<br><br>Pleural mesothelioma can develop in the lung's lining and the symptoms include pain and shortness of breath that becomes worse over time. These symptoms can also be caused by the accumulation of fluid in the lung (pleural effusion). Other signs of pleural mesothelioma include a bloody cough, abdominal pain and swelling in the abdomen, weight loss, fatigue and difficulty breathing. Peritoneal Mesothelioma, which is not as common, causes symptoms such as nausea, abdominal pain fatigue, fever and abdominal pain. [https://xn--hs0bj3fhvw.com/bbs/board.php?bo_table=free&wr_id=71047 Mesothelioma] of the tunica vaginalis is even less common and can cause pain in the testicular region, a lump inside the scrotum and loss in appetite.<br><br>The doctor will treat [http://www.mksteel.co.kr/bbs/board.php?bo_table=free&wr_id=17882 mesothelioma case] if it has spread to other parts of the body. They will apply various treatments and tests. The treatment options include chemotherapy, radiation therapy, and immunotherapy to kill or slow mesothelioma's growth. The treatments can be given in the hospital at home, at a clinic, or through the clinic.<br><br>A biopsy can also assist doctors to determine what kind of mesothelioma the patient has. There are three mesothelioma types: epithelioid (most commonly used), the sarcomatoid (second most commonly) and biphasic. The most popular mesothelioma type is epithelioid. They grow slower than other cancerous cells and are therefore less difficult to treat. Sarcomatoid cancer is more difficult to treat and can be spread quickly.<br><br>A person with mesothelioma should seek immediate treatment if they exhibit any signs or symptoms. It is imperative that they seek treatment right away if they experience any symptoms. A misdiagnosis can prevent patients from receiving the proper treatment and could give cancer more time to develop. The chances of a person with mesothelioma who lives longer is increased if they receive aggressive treatment.<br><br>Diagnosis<br><br>It is often difficult to diagnose mesothelioma because it is a rare type of cancer. It can take a doctor months or even weeks to determine if a patient has an illness that requires treatment. In addition to a physical examination and a medical examination, the doctor will ask questions about asbestos exposure and how symptoms started. The doctor might request an imaging scan. These tests can help to identify areas of problem in the lungs and chest cavity.<br><br>A biopsy is the primary test used to determine mesothelioma. This involves removing one small portion of the tumor, then examining it under an magnifying glass. The specialist doctor who examines the tumor will be able to determine whether it's mesothelioma, and what type of mesothelioma is.<br><br>There are three types of mesothelioma, epithelioid, sarcomatoid and mixed (biphasic). The cell type is important because it can affect the ease of the tumor to treat. Around 70 percent of [https://heartmatters.co/question/the-10-most-terrifying-things-about-mesothelioma-lawsuit-10/ mesothelioma law] patients are epithelioid cancer cells. Sarcomatoid cells resemble those found in fibrous tissue and are found in the remaining 30 percent of mesothelioma patients. The most deadly mesothelioma variant, called mixed mesothelioma occurs when it contains both epithelioid aswell as the sarcomatoid tumor cells.<br><br>Blood tests can be utilized to determine if the levels of fibulin-3 and soluble mesothelin related proteins, as well as osteopontin, are high. These substances are higher in mesothelioma compared to the general population. However the results of these tests are not enough to provide proof or disprove a mesothelioma diagnosis.<br><br>If a mesothelioma diagnosis is confirmed, the doctor could also require additional tests to work out how far the cancer has spread and how it is affecting the patient's overall health. For instance an examination of lung function will demonstrate how the lungs are functioning and aid doctors in deciding whether surgery is an option.<br><br>Other tests include other tests like a CT scan or MRI. A PET-CT scan combines a CT scan along with a positron-emission tomography scanner, which aids doctors determine if the cancer has spread and where it is situated. The doctor may also recommend an ultrasound to determine the extent of the accumulation of fluid around the heart.<br><br>Treatment<br><br>Patients with mesothelioma need to find the appropriate treatment for their condition. Treatment options include chemotherapy, surgery or radiation, as well as immunotherapy. Patients should consult the specialists of an experienced mesothelioma center in their local area to receive the best treatment possible.<br><br>Doctors can detect Mesothelioma with physical examinations, laboratory tests, and imaging scans. A patient can be taken to a specialist for more thorough testing or treatments, like the biopsy. A biopsy is a procedure in which a doctor removes a small amount of tissue for examination under a microscope. Mesothelioma is a cancer that develops in the mesothelium which is a layer of protective cells that covers organs within the abdomen and chest. It can expand into the bloodstream and travel to other parts of the body, where it could cause life-threatening complications.<br><br>In addition to a biopsied, doctors can also perform a CT scan of the chest or abdomen. These tests are used to look for signs of mesothelioma, as well as other diseases. They can also show the effect of the tumor on the surrounding organs. For example mesothelioma affecting the lungs can also affect the intestines and the heart.<br><br>The tests for blood can detect mesothelioma by looking for a substance found in blood. These tests are not always reliable, and do not replace a biopsy for mesothelioma. The early detection of mesothelioma lawyers ([https://www.mukti-pro.com/free/who-is-responsible-for-the-mesothelioma-lawyers-budget/ mouse click the following internet site]) can be crucial to increase survival rates.<br><br>Three types of mesothelioma exist depending on the type of cells that are created. Epithelioid is by far the most popular kind and is the most responsive to treatment. Sarcomatoid and biphasic mesothelioma are less responsive to treatment and have a worse prognosis.<br><br>Malignant pleural mesothelioma develops in the lung's lining called the pleura. Pleural [http://www.sohochung.com/bbs/board.php?bo_table=free&wr_id=180026 mesothelioma attorney] is treated by a doctor using surgery or chemotherapy. Two procedures are available for mesothelioma that is this type extrapleural pneumonectomy (EPP) and pleurectomy that includes pericardiectomy (P/D).<br><br>Doctors can utilize hyperthermic intraoperative chemotherapy, or HIOC to decrease the chance of recurrence of cancer after surgery. In HIOC, doctors insert chemotherapy drugs to fight cancer directly into the surgical site. Then, they rock the patient forward and backwards to bathe the site in hot chemotherapy fluids.

Latest revision as of 19:33, 4 October 2024

Mesothelioma

Mesothelioma is a form of cancer that grows in the linings of protection around organs, such as the abdomen and chest. It is usually caused by asbestos exposure, particularly for those working in industrial or construction jobs.

Early diagnosis and treatment are essential to a favorable prognosis. If mesothelioma can be detected early the patients are more likely to be successful.

Causes

Mesothelioma is a type of cancer that develops in the tissue which lines the chest and abdomen. In the majority of instances, mesothelioma litigation is malignant and is found in the lining of the lungs (the pleura) or the stomach's lining and the intestines (the peritoneum). It can also affect other tissues such as the tissues surrounding the heart (pericardial msothelioma), and the testicles.

Asbestos exposure is the main cause of mesothelioma. Asbestos is an assortment of minerals that contain tiny, microscopic fibers. Asbestos used to be widely utilized in many industries, including construction, shipbuilding and insulation. Asbestos exposure may cause mesothelioma symptoms for as long as 40 years after the last exposure.

The most commonly reported symptoms is difficulty breathing. This is caused by an accumulation of fluid in the space between the lungs and the chest wall. Doctors can identify the disease by reviewing the medical records of a patient as well as conducting diagnostic tests. They will look at the patient's X rays, computed-tomography (CT), and magnetic resonance imaging scans (MRI) to determine whether there is any evidence of asbestos exposure.

A biopsy is the main method used to detect mesothelioma pleural. In the course of the test, doctors will collect a small amount of tissue from the affected area to examine under the microscope. A biopsy can be carried out using two methods: VATS, a type keyhole surgery. Or, a needle that is inserted through a CT scan.

The signs and symptoms of mesothelioma are similar to those of other cancers which makes it difficult to determine. It's important to consult a doctor as soon as you notice any symptoms.

When mesothelioma first gets diagnosed, it's often in an advanced stage. Treatment options are limited. The majority of patients with mesothelioma of the lung die from complications of the disease, which include pneumonia and respiratory failure. Patients who have mesothelioma in different organs such as pericardial mesothelioma or tunica vaginalis may suffer complications that affect the heart or bowel.

Symptoms

Many of the symptoms of mesothelioma are comparable to the symptoms of other diseases or conditions that is why it may be difficult for doctors to establish a diagnosis. Patients might be asked about their exposure to asbestos. They can also request a chest X-ray or CT scan to look for problems with the lungs and chest. A biopsy is typically the next step. It is where doctors take a small portion of mesothelioma to test. A biopsy can be used to determine whether the cancerous cells are malignant.

Pleural mesothelioma can develop in the lung's lining and the symptoms include pain and shortness of breath that becomes worse over time. These symptoms can also be caused by the accumulation of fluid in the lung (pleural effusion). Other signs of pleural mesothelioma include a bloody cough, abdominal pain and swelling in the abdomen, weight loss, fatigue and difficulty breathing. Peritoneal Mesothelioma, which is not as common, causes symptoms such as nausea, abdominal pain fatigue, fever and abdominal pain. Mesothelioma of the tunica vaginalis is even less common and can cause pain in the testicular region, a lump inside the scrotum and loss in appetite.

The doctor will treat mesothelioma case if it has spread to other parts of the body. They will apply various treatments and tests. The treatment options include chemotherapy, radiation therapy, and immunotherapy to kill or slow mesothelioma's growth. The treatments can be given in the hospital at home, at a clinic, or through the clinic.

A biopsy can also assist doctors to determine what kind of mesothelioma the patient has. There are three mesothelioma types: epithelioid (most commonly used), the sarcomatoid (second most commonly) and biphasic. The most popular mesothelioma type is epithelioid. They grow slower than other cancerous cells and are therefore less difficult to treat. Sarcomatoid cancer is more difficult to treat and can be spread quickly.

A person with mesothelioma should seek immediate treatment if they exhibit any signs or symptoms. It is imperative that they seek treatment right away if they experience any symptoms. A misdiagnosis can prevent patients from receiving the proper treatment and could give cancer more time to develop. The chances of a person with mesothelioma who lives longer is increased if they receive aggressive treatment.

Diagnosis

It is often difficult to diagnose mesothelioma because it is a rare type of cancer. It can take a doctor months or even weeks to determine if a patient has an illness that requires treatment. In addition to a physical examination and a medical examination, the doctor will ask questions about asbestos exposure and how symptoms started. The doctor might request an imaging scan. These tests can help to identify areas of problem in the lungs and chest cavity.

A biopsy is the primary test used to determine mesothelioma. This involves removing one small portion of the tumor, then examining it under an magnifying glass. The specialist doctor who examines the tumor will be able to determine whether it's mesothelioma, and what type of mesothelioma is.

There are three types of mesothelioma, epithelioid, sarcomatoid and mixed (biphasic). The cell type is important because it can affect the ease of the tumor to treat. Around 70 percent of mesothelioma law patients are epithelioid cancer cells. Sarcomatoid cells resemble those found in fibrous tissue and are found in the remaining 30 percent of mesothelioma patients. The most deadly mesothelioma variant, called mixed mesothelioma occurs when it contains both epithelioid aswell as the sarcomatoid tumor cells.

Blood tests can be utilized to determine if the levels of fibulin-3 and soluble mesothelin related proteins, as well as osteopontin, are high. These substances are higher in mesothelioma compared to the general population. However the results of these tests are not enough to provide proof or disprove a mesothelioma diagnosis.

If a mesothelioma diagnosis is confirmed, the doctor could also require additional tests to work out how far the cancer has spread and how it is affecting the patient's overall health. For instance an examination of lung function will demonstrate how the lungs are functioning and aid doctors in deciding whether surgery is an option.

Other tests include other tests like a CT scan or MRI. A PET-CT scan combines a CT scan along with a positron-emission tomography scanner, which aids doctors determine if the cancer has spread and where it is situated. The doctor may also recommend an ultrasound to determine the extent of the accumulation of fluid around the heart.

Treatment

Patients with mesothelioma need to find the appropriate treatment for their condition. Treatment options include chemotherapy, surgery or radiation, as well as immunotherapy. Patients should consult the specialists of an experienced mesothelioma center in their local area to receive the best treatment possible.

Doctors can detect Mesothelioma with physical examinations, laboratory tests, and imaging scans. A patient can be taken to a specialist for more thorough testing or treatments, like the biopsy. A biopsy is a procedure in which a doctor removes a small amount of tissue for examination under a microscope. Mesothelioma is a cancer that develops in the mesothelium which is a layer of protective cells that covers organs within the abdomen and chest. It can expand into the bloodstream and travel to other parts of the body, where it could cause life-threatening complications.

In addition to a biopsied, doctors can also perform a CT scan of the chest or abdomen. These tests are used to look for signs of mesothelioma, as well as other diseases. They can also show the effect of the tumor on the surrounding organs. For example mesothelioma affecting the lungs can also affect the intestines and the heart.

The tests for blood can detect mesothelioma by looking for a substance found in blood. These tests are not always reliable, and do not replace a biopsy for mesothelioma. The early detection of mesothelioma lawyers (mouse click the following internet site) can be crucial to increase survival rates.

Three types of mesothelioma exist depending on the type of cells that are created. Epithelioid is by far the most popular kind and is the most responsive to treatment. Sarcomatoid and biphasic mesothelioma are less responsive to treatment and have a worse prognosis.

Malignant pleural mesothelioma develops in the lung's lining called the pleura. Pleural mesothelioma attorney is treated by a doctor using surgery or chemotherapy. Two procedures are available for mesothelioma that is this type extrapleural pneumonectomy (EPP) and pleurectomy that includes pericardiectomy (P/D).

Doctors can utilize hyperthermic intraoperative chemotherapy, or HIOC to decrease the chance of recurrence of cancer after surgery. In HIOC, doctors insert chemotherapy drugs to fight cancer directly into the surgical site. Then, they rock the patient forward and backwards to bathe the site in hot chemotherapy fluids.